Both clubs won their encounters against rivals Kaizer Chiefs and Supersport United.
Orlando Pirates thrash Amakhosi 1-0 as they grabbed a late three points at the FNB Stadium, while Mamelodi Sundowns eased past Pretoria rivals and Supersport United beating them 3-0.
The Buccaneers and Masandawana look to earn points over each other as Pirates trail Sundowns by six points with a win rate of five out five past games while Pirates has lost only one of their previous five encounters.
Watch: Mamelodi Sundowns v Orlando Pirates Top Goals